What are the limitations or challenges of a systematic review?

Posted: March 9th, 2022

Explain the importance of systematic review and meta-analysis for evidence-based practice.
What are the limitations or challenges of a systematic review?
How can one overcome such limitations or challenges?
Offer an example of a situation when a systematic review and meta-analysis were one of the defining points in the decision-making process, and when without it the decision might have been incorrect.

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